I don't recommend Penthouse Pack or Special Ops Vehicle Pack. Penthouse Pack just adds 4 more girls to your gang customization. The Special Ops Vehicle Pack just gives you a tank, N-Forcer, and VTOL that are the same as the ones that become available later in the main story anyway, except they're purple and have Saints logos on them.
I liked the bloodsucker pack, the healing can be useful in a pinch. I never really used the neck-snapping move before getting the DLC, so I can't remember how much worse it really is. I usually just held onto my human shields or threw them instead of executing them.
The Unlockables Pack can be neat if you really can't decide between two rewards or want them early.
I didn't buy the Invincible pack. Once you get all the upgrades for your character, you'll have infinite ammo and be almost unkillable anyway. I guess there's the Infinite Mass and Super Explosions cheats, but they don't interest me. I'd probably play around with them for about 5 minutes and then forget about them.
I change my character's appearance a lot, so I like the clothing packs. The vehicles are alright, I used the Sexy Kitten, Angry Tiger, and Nyteblayde vehicles once in a while. I didn't use the bonus weapons much at all, except maybe the sniper rifle from the Money Shot pack.