When was the last time you honestly laughed out loud at an intentional joke in a game? I mean proper laughed out loud not just being overcome with the urge to write "lol".

About a week ago, several times, while playing Goat Simulator. Gloriously hilarious game. :)

Edit: Ah, no, the last time was actually while playing Portal 2 a few days ago. :)

When I played D, I exploded with laughter at the big reveal at the end. But that was not supposed to be comical.

I think HARVESTER is the most funny game that I know - but did I actually laugh at it? Yes, I think I did!

No One Lives Forever (both) is my favorite game series because it is hilarious. I laughed countless times when I played those games. :)

I also finished Day of the Tentacle a few days ago, that's a great one!

An old game I'd never heard of? You've made my day! :D

This. I mentioned it yesterday in the NOLF thread but whenever I hear those two guards start to discuss which terrorist organization has the best employee benefits I fall out of my chair.

I also laugh at "Horny little rabbit." from Shadow Warrior but then people would expect me to laugh at that. :P

Damn, I was about to write Oblivion because of some of the voice acting, and glitches, but nope, probably not intentional.

Guacamelee has a nice sense of humor, but I don't think it's quite laugh out loud funny. Damn, I'm not sure if I can think of anything that meets that fully meets that criteria.

Far Cry: Blood Dragon and Borderlands 2 had me laughing heartily often enough.

The Bard´s Tale

Probably exploding children in the Fallout games or when I was mowing down innocent people in Modern Warfare 2... it's always more fun when they're innocent.

Does that count? :P

Crusader Kings 2 when I had a bastard with my brothers wife that he thought was his
The game a high ability for hilarity

Anachronox. I picked it up during the winter sale, not really knowing anything about it and I was blown away by how uproariously funny that game's writing is.

Risen 2, playing as a voodoo pirate.

I barely had the chance to start it, but Simon the Sorcerer -- Even the manual had me laughing out loud! XD

Damn, looks like I am an emotionless bastard compared to everyone else. Can't remember if I have ever laughed out loud at an intentional joke in a video game.

There have been lots of times where a game has put a smile on my face but that is as far as it goes.