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For me, Witcher 3 was running fine in 1.8 and earlier versions, but when I update it to 1.10 and start it, it stays in a black screen permanently. Has anyone else had this issue?
Sorry. Can't help you. But perhaps you will have more luck to find a solution if you would ask this question on the Witcher 3 GOG forum:
http://www.gog.com/forum/the_witcher_3_wild_hunt/page1#1445203503
Good luck!
You may try renaming d3d11.dll to something like d3d11.bak in \The Witcher 3 Wild Hunt\bin\x64 path or reinstaling VC++ redistributables.
Good luck! : )