timppu: Are you talking about the 16-bit Windows games which needs 32bit Windows XP or older to function properly?
Where are you playing it, on some retro-PC?
I presume it is not sold on GOG, at least I didn't find it with a fast search...
First question: yes. I'm playing Stars! (full game version 2.7i) on a modern Win10 PC (you can use DOSBox For Windows or another 16-bit emulator or VM to run it), and. And it's not sold on GOG.
I was curious to see how I like Stars! today (still very much!), and standard games work well. Custom race generation and launching custom games work, too, except when I want to change the players, where the game won't let me change anything.
I'm hoping to find players on this GOG forum, who not only remember Stars!, but also have some experience with setting up custom games - why not give it a try? I'll ask the same question on the Stars! Autohost forum, too.