I have a CPU: 1.8GHz Intel Core i7-8565U (quad-core, 4MB cache, up to 4.6GHz)
Graphics: Intel UHD Graphics 620.
RAM: 8GB DDR4.
Screen: 13.3-inch FHD (1,920 x 1,080) touch panel (WLED, IPS)
Storage: 512GB SSD (PCIe, NVMe, M.2)
Ports: 2 x Thunderbolt 3 (USB-C), 1 x USB 3.1, 1 x microSD, 1 x 3.5mm audio jack.

Why can't I play Obduction? Is there a setting issue?

It would be helpful to know what exactly it does when you try to load it. However I can say that your graphics card isn't up to the task. If the game did run, it wouldn't run well.

From those specs you most likely have a laptop or an all-in-one. And unfortunately, that means you won't be able to upgrade the graphics card. If by some chance it is a desktop, you could get a new graphics card and fix the issue.