I was about to say Hellblade, but I see it made it to your list.
So then... Gris, Night in the Woods, Child of Light (what a soundtrack it has!, Limbo, Celeste, Fran Bow, Outlast, both Manhunt games (fair warning: they're extremely disturbing). I guess The Last of Us can be considered as well, to a certain extent.

Darkest Dungeon?

The Town of Light and Martha is dead seem to fit your description very well even though they seem to be mostly story focused. Read that as: Little actual gameplay, sometimes also called 'Walking Simulator.

On top of that insanity is pretty much a theme in all Cthulhu games so Call of Cthulhu, Prisoner of Ice and Shadow of the Comet are worth a look as well.

That also includes games that are not Cthulhu in name but still take the Cthulhu mythos as its theme like The Last Door Season 1 and Season 2.

Maybe not the most obvious choice, but Mad Max.
Also, Spec Ops: The Line.

Lylian Episode 1: Paranoid Friendship
Keep In Mind

(I'm not recommending them as good indie games, but they fit the themes.)


If you have Neverwinter Nights, there is a fan-made module taking place in an asylum, where you have to enter the inmate's minds in order to fix them (it predates Psychonauts by one or two years). This one I do recommend.
Excrucio Eternum

I already have Outlast and I put a few of those on my wantlist, thanks! Manhunt isn't easily available in Germany though, I'm afraid :-/


Have it in my collection, not played yet though. I actually like walking sims, so I'm ok with that ;-)


I put Martha is Dead on my wantlist, thanks!
I have the old CoC-game, I guess the Cthulhu-mythos is depicting a very unspecific, undefined kind of "insanity" that doesn't differ a lot throughout the games?


Thanks! I have Neverwinter Nights, so I'm downloading this ASAP ;-)

In some ways, Disco Elysium fits here.

It takes reading between the lines and/or reading external resources to put it together, but Braid.

There are a ton of visual novels that work with it to varying degrees (Growing Up has some of the characters you interact with struggling with various issues to different degrees). Many horror games as well (which inclutes Cthonic ones). Amnesia, famously.

Deal with vs depict has a big difference. Many games just touch on it with a side character. Other games have it as important element. Some do not do it respectfully.

Aye, Alice is excellent, and Psychonauts, while silly, is as fitting as it gets. Nobody mentioned Max Payne, Mnemosyne, Yume Nikki, Alan Wake, Observer, The Path and The Void yet?

There was also an old, increasingly surrealistic and macabre point and click asylum adventure that I would recommend and love to replay if I could remember its name to begin with, and another point and click adventure about a girl offing her parents, getting locked up and trying to escape the institution, that I also can't remember the name of.

For the (fictional/exaggerated) psychiatry aspect:
Batman: Arkham Asylum
Edna and Harvey: The Breakout / Edna and Harvey: The Breakout - Anniversary Edition
Edna and Harvey: Harvey's New Eyes

Silent Hill 2 is quite famous.
Hard to find but Eternal Darkness has a sanity meter that causes negative effects when it gets too low (saves deleted message, blue screen of death, etc).
Clock Tower games

It's been on sale for as much as 90% off.


This War of Mine.
Characters have to deal with war. It takes its toll, both physically and mentally. Currently on sale at -84% or -80% for the base version.

Eliza
A sci-fi visual novel about an Ai counseling program. I haven't played it yet, but it's on my wishlist.

I can absolutely recommend Night in the Woods.

Not on GOG, but is available DRM-free:
Celeste
https://mattmakesgames.itch.io/celeste

Celeste is both a wonderful precision platformer and a look into mental health issues.

(Also, it goes without saying, but the games mentioned in this thread may contain triggering content, like discussions of mental health issues, including things like suicide; if you're not in a good state of mind, you may want to pass on these games until you are.)

Do you mean Sanitarium?


I heard the name "Edna and Harvey" before, but I had no idea, what these games were about. Added to my list, thanks!


Silent Hill 2 is amazing, still got it on my PS2. Eternal Darkness was a Gamecube game, iirc?


I read about that in this context before, I need to look into that game. A platformer dealing with this kind of a topic is quite rare, I guess.