Fairfox: imma talkin' outside rpg thangs which you can grind or whatevs, 'coz i mean i guesses you get oot wut you put in?
Actually, this is even an issue in RPGs. Sometimes, you hit a wall where you have to spend a while leveling up before you can continue. Sometimes, you hit an even harder wall which can't be solved, at least not in a reasonable amount of time, by leveling up.
The final boss of Paladin's Quest is an example of the latter. (That particular boss is much harder than anything else in the game, to the point where I would consider that boss to be *too* hard.)
Also, the Ice Cave in Final Fantasy. I am playing the PSX version on Easy Mode, and in the Ice Cave my party still got slaughtered multiple times by mage ambushes. Keep in mind, this is on *Easy* Mode, so my party was higher leveled than normal for that part of the game. (It's a good version this version has the Memo save; imagine how many players of the original NES game quit there out of frustration!)
A more recent example is Dragon Quest 8, which has one particular boss that is significantly harder than any bosses up to that point.