This is not a for-everybody tutorial. I finally got the game to work, and this might be helpful to people who need that extra step.

When I loaded the game I got a poorly lit interface with really horrible in-game graphics, and some other nasty glitches. Lots of red and green. That's the problem. Here was my solution:

I got the game to render properly by installing 'winetricks'. This tool lets you install dependencies that the game needs to work properly.

Run 'winetricks', and select install a game. You don't see 'frostpunk' listed. So cancel. The next screen lets you select other options. Select "Install a Windows DLL or component."

I installed:
d3dx11_42
d3dx11_43
dxvk

(DirectX11 is the dependency I needed to install.)


NOTE: Probably only DXVK needs to be installed.
NOTE II: This only fixed my problem. A rendering issue.
NOTE III: I'm not tech support. This was the one item I was missing, a driver emulation. I'm posting this here for anyone with the same problem. Your problems may be different. I'm not available to answer questions, but I hope this helps, or points you in the right direction.