'Far Cry 2' crashes to desktop on high-range display settings, shortly after the gameplay start or sometime into the game. I have seen this problem mentioned on other forums as well, therefore I doubt it would be only the problem on my specific machine. I have run a debug mode and what it told is that D3D has problem with memory allocation for textures. I run the game with display settings maxed out and only the textures set low, thusfar it has not crashed, though needs further testing.

IIRC setting the large address aware bit fixed most of the crashing for me.

I do guess 'Far Cry 2: Fortune Edition' is a 32-bit only app?

Yep.

Dr Google reports some say Lutris and PROTON have ways around that, to set an environmental variable. Otherwise, some suggest selective patches for executables.

I think I used this https://github.com/randomstuff/pe-set-laa

Looks simple enough to do in a hex editor too.