Unfortunately, Fallout 3 GotY still does not work for me, despite the patches from GOG. Whenever I try to start the game, the screen turns black for a second, then crashes back to desktop. It doesn't matter whether I use Launcher or the f3.exe.
Verify/Repair in Galaxy didn't have any effect.
Reinstalling/Repairing DirectX didn't have any effect.
Patching Audio & Video Codex didn't have any effect.
Installing G4WL didn't have any effect.
Running it as Administrator and/or in compatability mode (Win 7/8, Win Vista SP2, Win XP SP3) didn't have any effect.
Tried different resolutions, quality settings, turned off my second monitor via display settings, tried windowed and fullscreen - you guessed it, no effect.
System is an AMD Ryzen 5 1600 with 16 GB RAM and ATI Radeon RX580. All drivers and the OS are up to date.
Edit: The issue could be solved deleting the settings from my user directory and using the Fallout: New Vegas Crash Fix from the Nexus page.
Post edited June 06, 2018 by Alameachan