Downloaded game and played maybe an hour. Realized i had downloaded to SSD and wanted to move to my d: SATA drive. Afterward, game load screen comes up, i chose continue game/ load game and get to spinning circle screen and game never loads. Tried new game, after opening FMV game closes out/crashes... uninstalled and re-installed and get the same deal... i've tried running in different compatibility modes, i've tried changing to lower graphics settings, still cant get game to play EXCEPT for an autosave that had me in a building in Goodsprings... however if i try to leave, pip-boy, anything game closes. what is going on?

MSI Raider 9SE
Intel I7 9th gen
RTX 2060
windows 10

I'm having problems too.

Came back to continue this game after a few months, loaded my game, walked 3 steps and pressed tab to check the quest log and the game crashed. Now it crashed every time in the first loading screen

I tried the verify options and it didn't work... might try reinstalling the game later today and see if that helps

edit: reinstalling didn't work either, game still crashes in the first loading screen after pressing "continue"

7 times in a @!#$ row trying to trade with the Gun Runners, having it crash just before I finish the transaction.

Tried to disable GOG overlay?
Edit: tried to play my 1 year old copy of the game with all kinds of mods, runs like it used to.

Is there a way to give a + for your post? That did the trick for me. THANKS!

@edit: found it!