Recently I tried "Tale of Two Wastelands" but gave up on it as overmodded and went back to primarily vanilla game with bug fixes with a few Quality of Life updates.
But I still looked to their guide for some essentials:
https://thebestoftimes.moddinglinked.com/essentials.html I'm using Vortex as my mod manager, and these are the Mods I have installed:
https://imgur.com/vCNVGBG Highlights:
YUP: This is the major bugfix patch. Must have.
Realistic Wasteland lighting: Makes much more beautiful lighting and skies and has negligible overhead.
JIP improved recipe menu: If you are going to hand load bullets or convert energy Ammo, you need this. Lets you process all at once instead of small batches.
Stewie Tweaks: This can change a LOT. Too much really. I only use it to fix game controller aiming and lower the deadzone.
I have no idea what affect achievements, as I don't care about them and don't use Galaxy.