Hey Guys, When I try and play Fallout 4 I am able to use my keyboard and mouse when I am on the game menu and character creator. As soon as i go into the game my mouse stops responding and so does my keyboard except for the funtion keys at the top and Esc. When I click on escapse I can use my mouse and keyboard with no issues. I have tried going into the fallout4prefs file and setting gamepad to "0". Any other ideas what could be causing the issue?

If you have a gamepad, unplug it. Double check that you didn't leave one plugged in.

Hi , No I don't have a game pad connected.