After 5 hours of gameplay, now it always ending on a infinite loading screen. This is not new, part of the long list of decades of never fixed problems that Gamebryo->Creation Engine have, a long heritage of shit tech.

Any tip?

Try starting a new game. Once you get control, load the latest save from your previous playthrough. That should be sufficient to get past this highly annoying bug.

Thank you for the explanation, I am going to try this tip when I reinstall the game.