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Install and initial hour or so gameplay is as expected of a mod this size, however the crashes now are to the point its unplayable in current state. Hoping the devs are able to fix this as I can envisage many many hours of adventure. I'll be waiting a patch I think. I don't mind the odd crash, but the amount now is gamebreaking.
I had to do a few things to get it to stop crashing:

1.) Putting this into Falloutprefs.ini (in your Fallout folder do a search for 'ini'):

[NVFlex]
bNVFlexEnable=0
iQuality=0
bNVFlexInstanceDebris=0
bNVFlexDrawDebris=0

2.) Turn off weapon debris within the in-game options.

3.) Installing the Buffout mod from Nexusmods (which also requires several other downloads that it will tell you about).