As per title,
I'm trying to run the game (both patched and un-patched) but it does not even start.
I'm on OSX 10.11, general troubleshooting hasn't helped me in the slightest.
Anyone able to help?

Contacted GOG today, and they told me something strange.
Try to disconnect and/or delete any printer/scanners you may have connected to your computer, both wireless and through cable.
Solved the problem for me :D

Contacted GOG today, and they told me something strange.
Try to disconnect and/or delete any printer/scanners you may have connected to your computer, both wireless and through cable.
Solved the problem for me :D

Thanks for answering. I tried following your instructions but the game still crashes instead of loading. :(

The problem seems to be the WineSkin integration of the CUPS printing daemon.
But, you can update the Wine engine and set some screen options, and voila! It works!

I got it to run, here's how you do it!
https://www.gog.com/forum/evil_genius/howto_get_the_game_working_on_mac_os_1011_el_capitan