dikembe5: I have the exact same issue described by others in this thread. My card is RX 6750XT, up-to-date drivers, and the game fills up all 12gbs of VRAM after fast travelling, but I can recreate this by just entering and exiting Whiterun a handful of times. After that what happens in the first post happens to me as well, same RAM specs, and eventually it gets choppy and I get an unending loading screen, forcing me to kill the Skyrim process (using all of my RAM) in task manager.
Can anyone else confirm if the Vulkan solution mentioned above addresses this entirely?
It works very well for me. VRAM on my GTX 1080 stays around 4GB constantly. I mean, it fluctuates but the memory leak definitely isn't present. At least it doesn't seem to be. If you install DXVK, you may get some stuttering at first because it is creating its own cache file but it'll clear up. Performance seems to be the same, too. I've used DXVK for other games, it's a great mod but requires trial and error as it won't work for everything.