Since I am a recent convert to playing Descent with a KB+M (appearantly A_Future_Pilot plays Descent with this and from some googling so do a lot of people apparently) I have decided to post a config I made that works for me.

Note: Some keys like Left Alt affect your ability to access menus, I just used right Alt and right Shift also I will indicate some D1 and D2 differences.

Note 2: You have to clear the weapons select keys to use 1,2,3 for cycling or you can rebind them to the numpad or whatever.

Accelerate: W

Reverse: S

Slide Left: A

Slide Right: D

Slide Up: Space

Slide Down: Left Shift

Pitch Up: Left Alt

Pitch Down: Left Ctrl

Turn Left: Q

Turn Right: E

Automap: Tab

Cycle Primary: 1

Cycle Secondary: 2

Fire Flare: F

Drop Bomb: B

Descent 1 Specific Keys:

Rear View: R

Descent 2 Specific Keys

Rear View: G
Afterburner: R
Toggle Bomb: 3
Headlight: H
Energy to Shield Converter: T

Mouse (Applies to D1 and D2):

Pitch = X-Y Axis
Fire Primary = MB 1
Fire Secondary = MB 2

Feel free to use this as a template to make it your own, feel free to ask questions, feel free to do anything you want.