I had the same problem and managed to solve it. Deponia 3 crash while showing the language select screen with the following Windows error message:
Problem signature:
Problem Event Name: APPCRASH
Application Name: deponia3.exe
Application Version: 1.0.0.1
Application Timestamp: 52544e13
Fault Module Name: ntdll.dll
Fault Module Version: 6.1.7601.18247
Fault Module Timestamp: 521ea8e7
Exception Code: c0000005
Exception Offset: 00037b34
OS Version: 6.1.7601.2.1.0.256.48
Locale ID: 1031
Although on one occasion it showed "openal32.dll" as Fault Module Name, which helped me solve this annoying problem:
1. Try updating your soundcard or chipset audio driver (didn't help in my case)
2. Try renaming the "openal32.dll" in your Goodbye Deponia folder to "openal32.dll.bak" so the game uses the system library.
Step 2 did help in my case and everything is fine so far (haven't played much). If neither helps, undo step 2 and contact official support (support@daedalic.de).
Post edited June 23, 2014 by EraDKtor