You need a good rig for all the bells and whistles and personally, I wanted the complete package. Been salivating for this game since it's opening trailer almost a decade ago. So if you're not into this genre, I would hold off until a platform for this game on ultra settings becomes affordable. It is a visual and narrative marvel that you really should experience at it's best if it's at all possible. It's meant for a cutting edge platform for now. I don't know about you guys but I couldn't get Dell to give me Cyberpunk FPS data on their Alienware series. Read between the lines. I'm not even sure if the nvidia 30 series can pull off all it can do. Still, an 11th gen intel with rtx 3070 8gb and an ssd seems to play this pretty smoothly with raytracing and dlss on. I'm almost near the end of a playthrough starting on version 1.3 after something like 130 hours and have yet to experience a crash. Glitches though unfortunately do happen and may stack up the longer you play in a single sitting. Shutting down the game and restarting seems to settle most issues though. And I save often. Also, get your brightness settings set correctly. Do not rely on default in-game brightness settings. This game does not have flashlights, or night-vision optics. :/ Not game breaking but...yeah, you need to play around with in-game brightness settings.
To be fair, I'm not sure if you'll enjoy this as much as the original Mass Effect on a narrative standpoint, given that that was a pretty brilliant trilogy of games with years of development, while this one is still in (hopefully) only part 1 and without DLC. I still love what I've seen so far in Cyberpunk. For example, QOL-wise they have several tv and radio channels. I'm especially impressed with the TV channels as they actually have little TV programs. You might want to take the time to watch them between missions as they change as you progress the story, to indicate current events. They also bring back witcher's trademark changes to story development depending on what order you do gigs or whether you do certain side gigs before the main gig. One major thing I would recommend to newbies if they don't intend to do multiple playthroughs: do not do ANY side gigs before doing the main gig, the Heist. If you need to grind levels and gear, do blue non-story assault cases or NYPD wanted cases that do not have story, preferably not getting too close to the (!) symbols that indicate something of interest there. You know you're too close if somebody calls you with details of a job and quest information comes up. I hope there's no time limit to these side gigs but I hate taking chances and losing out on story content.
I've played Assassin's Creed Odyssey and Watch Dogs 2 and count them among the best sandboxes I've played. Odyssey had a ship which you could upgrade and crew with various officers and crew archetypes. And you could listen to sea shanties. You also have little repeating side gigs complete with npc dialog for minor rewards. You could waste a whole day just doing everyday chores like this and completely forget about the main quest. Watch Dogs 2 had some nice cyberpunk elements like hacking phones to pick up snippets of NPC life and getting rumors of ongoing in-game events. Also actually hacking cars and using drones. I also love the repeating taxi missions as you can hear npc stories and get different results depending on your performance. You can even repeat all Main Story missions on demand post-game. And, well, it's set in San Francisco. Nuff said? Night City is really gorgeous but there's still some polishing to do and I really would like more in it from a sandbox point of view. Stuff that makes me come back to it just to spend time. I have limited access to the internet so offline mode is really essential to me.
Anyway, so far I'm loving this game. I intend to do at least 3 playthroughs with each lifepath. Maybe up to 6 if gender has major effects too. Waiting for a datamine for any hidden content in the game. I know I've missed at least one little unmarked side gig involving a rollercoaster that has an activation window. Can't be activated before a certain event and after yet another event. I hope missing the quest flag doesn't negatively impact anything. :/
Hope this helped.