At first every sound seem to be coming from the correct speakers in 5.1. After playing for a while the sounds start coming from the wrong speakers. Sounds that should come from the front come from left and some sounds that should come somewhere from the front come from the back. It's really annoying. For example, shooting sounds come from the rear. Even when I first booted the game up the menu music suddenly started to come from the rear speakers. Closing and reopening the game fixes this but this is a problem that has occurred every time I have started playing.

Specs:
Win 10 64bit
i76700k
Nvidia 1070
Sound Blaster ZX

I'm not 100% sure if this a problem directly tied to Cyberpunk 2077 but it is the only game that I have this problem with.