Hi, first time player here..Just remembered this game from my kid days and realized I never even saw it running, only saw the cover pic everywhere when it came out. Now I wanted to try it and have quite some performance issues. No Remorse had terrible FMV tearing but it was easily fixed by changing DOSBOX to OpenGL, but the game itself...it has a lot of tearing, freezing and shuttering, resulting even in sound skipping, especially when screen advances to next location...Any easy way how to improve that? Or should I simply wait for full ScummVM support, what do you say?
Playing on very modern ultrabook, 4k screen, i7, 16GB RAM, weak but dedicated nVidia GPU.

You could try overlay or ddraw, opengl never gave me anything than performance issues.
You can also try increasing the cpucycles.

Lastly you can try using another dosbox build like dosbox x or dosbox staging which I'm told have v-sync options build in.

I tried to mess around with dosbox.conf, no big help. But I did try it on my gaming PC, recent fast i7 + GTX 1080 and it works smoothly and ok. Apparently, that's what we need to emulate i486 these days....

What fixed it for me was changing the scaling engine (under advanced settings in the graphics mode setup from the GOG client to hq3x. Runs like a champ on my older i3 office computer.