I encountered a game breaking bug during chapter 5. After dealing with the two side quests (the mold and the clocks), I went for the main quest. But upon arrival at the panopticon entrance the dialogue with the supervisor wouldn't work. The characters were staring at each other without dialogue.

After many attempts I decided to restart the chapter and go directly to the panopticon. Now the dialogue starts but it's not the right one, the supervisor is talking of a TV. I checked on youtube and Jesse should have asked about Dylan first, leading to the TV quest. However, since this part of the dialogue never happens, the door to the panopticon remains shut and I can't continue the game.

Is there a way to rectify this ? After 30+ hours, I don't have the courage to start the game from scratch. :(

I managed to get rid of this bug by deleting some save files! :)
The problem seems to reside in the way the game keeps track of collectibles, chests, powers.

- backup saves
- launch the game and restart the chapter having issues
- exit the game
- go to Documents/My Games/Control/Saves and delete the files that have been modified just minutes ago when you restarted the chapter.
- go back to the game and restart chapter again, it should work properly now.