UPDATE:
I tweaked it and figured it out!

ORIG MSG:
Hi guys,

I know it's 22050Hz sampling at best (played the original back then) but the default sound chosen for the DosBox launcher is just bad. It's NOT STEREO and it HISSES pretty badly, making the sounds a chore to listen to. - And I really used to looooove Bloods sound-art.

I tried playing with the BloodGOG config file (with text editor) and also the setup file (Sound Blaster / Midi etc.) but to no avail - it does not even seem to make a difference at all.

Can anyone pleeeaaaaase help me? <3

Thanks,
Freylis