Maybe a dumb question but is Genocide easiest or hardest?

Genocide - Easy
Homicide - Normal
Suicide - Hard

But even easiest enemy can be devastating if you don't have any armor and armors in that game are often found in secret places, from some enemies or in limited number. Also you will hate Shikari warriors and Naga boss with burning passion. It's possible even with Ishmael on Suicide, his max health is 100 though... Reloading save during boss battle is useless because in many cases it's health bar will go reset to full but you won't get your wasted ammo back and all remote, time or proximity bombs after reload are inactive and not-explosive.