PraetorianWolfie: Exactly. You could check their creation date to find the one that you recently saved, which I supposed should be the one with the issue.
murdocmcmurder: Here you go.
https://drive.google.com/file/d/1LflZS3Wz3Xng-r7j4UDRN_aeR4OoWYis/view?usp=sharing Ok, I think I see the issue. In your playthrough McCoy seems to have missed a few clues that would have made him suspicious of Guzza, so that he could discuss about him with the twins.
Most of those clues are no longer attainable in this Act (some are not attainable due to choices McCoy made earlier in the playthrough).
However, it's still possible to get one clue that will allow McCoy to ask the twins about Guzza. The clue is acquired by clicking on the torture chair that he was strapped to by the mercenary cops before Steele saved him. McCoy will describe what he knows about this type of chair, and then you can go to the twins and discuss about Guzza and the DNA trade.
Let me know if you need more specific details on this.