Hello fellows, I'm having no luck trying to run the bundle on a Mac.

The symptoms:
1. Game setup window appears @ launch (where you can select things like if the game runs on a window or full screen as well as the audio devices and such.)
2. I select the proper settings (I've mostly fiddled around trying both DirectDraw & Direct3D)
3. I choose "Save & Run"
4. The application runs and absolutely nothing happens

The process:
1. Downloaded the game using the latest GOG Downloader
2. Mounted the image
3. Copied Blackwell Bundle folder to Applications
4. Launch Blackwell Legacy
5. System requested I install X11
6. I install X11 and log out and back in as requested
7. Launch Blackwell Legacy once more
8. What is listed in The symptoms happens

Any help would be entirely appreciated. I've tried the GOG troubleshooting page but at no point is neither the installer nor the application requesting access as an assistive device... so I can't grant it to it.

You could try enabling access for assistive devices and applications afterwards:
http://support.apple.com/kb/HT6026

The problem with this is that, since the applications never requested access, they are not listed there and thus I can't enable access for them in that menu. I do not know a way to manually give access without the application asking for it.

Thanks for the ideas, keep em coming.

Will do. You fine fellows will be receiving a message from me shortly. Thanks for the assistance.

Note: I'll update this topic with any new developments in case someone else has this issue.