After a recent patch I noticed that the option to crush astral-touched tadpole was removed. Was this intentional? For me, this is a game-ending change or bug since I did not want the use of the astral-touched tadpole forced on me. Since my character is not wisdom-based, I had to reload many times to try and roll a natural 20 to avoid changing.

Larian removed it to force the change yes... you have lots of choices in Bg3 but few of them actually matter and without a sucker the ending kindo breaks

I haven't even noticed that option in the first place. I have only completed the game once, but am well on the way in my second playthrough. Both times I have yeeted the astral-touched tadpole out of the way as soon as the squidman gave it to me.

The option to crush it is still there but not until it is in your inventory. I don't know why it was removed before this. It seems unfair to players who don't want the tadpole.