Wbino: I'm two hundred hours in about to start chapter three and I have an urge to restart.......
There's a **TON** of content in Act III... so if you're super annoyed with something you did and want to go back and try another way, I guess that's an option because you'll be playing in that world for a while yet. If it's just character class/level decisions, you can pay Withers to re-class any of your characters. If it's storyline stuff, then you might be stuffed... there are a lot of decisions that you make with rippling consequences that can't be unmade.
I'm on my second playthrough, so technically that's a new start. Probably not what you're thinking.
Honestly, if you're going to play through the whole thing again, maybe finish out the game with this character and then replay with complete hindsight, rather than only having hindsight of the first 2 acts.