Has there been any luck in finding a fix for this bug? It's making certain areas of the game a real drag.. I tried experimenting with nGlide, but all that liked to do was either crash the game on startup, or run the game at 15fps.

Weirdly, I know I didn't have this issue several years ago when I was playing this game (on a previous machine).. surely something can be tweaked/done to fix this..

Attached a screenshot of the elevator in the Platform area of South Anachronox to give a dramatic example.

I have this problem too on my GTX 1050 (2GB) but didn't have it on my old PC with GeForce 2.
I've never searched for any fix though. It doesn't bother me much as it only seems to be present in Platform Area.