Hmm. I guess that must have been Alan Wake (because of the infuriatingly bad controls) or Giana Sisters (because it gets quite hard towards the end).
The difference is, I went back to Giana Sisters. 'Being hard' towards the end is part of the game design in old-school jump-n-runs and it is a good game that motivates to overcome the frustration and triumph in the end. While in the case of Alan Wake the frustration just came from unnecessarily bad game design. And that is not motivating at all. You know it will be just as bad the next time you start it. So I never went back to Alan Wake.

But in the case of the most rage-inducing game I know, rage-quitting would have been pointless because the infuriating thing happened right at the end. I had to check online whether that was really the end of the game, because I couldn't believe anyone would write such a cr*p. But it really was the ending, the writers apparently hated their players and took an effort to write the most unsatisfying, screwed up ending ever and I, consequently, uninstalled Divinity II.

Giana Sisters: Twisted Dreams

Worst game I've ever played. The final boss is impossible to beat when you randomly die because his attacs miss you?! Waste of time and money. Could have been a decent platformer with great artwork and soundtrack...

I've finished Alan Wake five minutes ago and I know exactly what you mean. For me the worst part was when I was feeling that I had been cheated or at least not been adequately rewarded. For example: I was smart and instead of shooting Takens I ran to the nearest safe haven which was not an easy task. But I succeeded, saved some ammo and was proud because of it. I saw some ammo lying just there but I couldn't take it due to the stupid item limit. Not good but I decided that I would just kill next Takens and come back to collect the ammo. And then what happened? A small ledge on my way. I had to drop and there was no way to come back to the previous point. I HATE IT! The way the game limited your movement was so unrealistic that I could have regequited it many times! What's the point in encouraging the player to save his ammo when he cannot accumulate it for harder battles anyway? That's just ridiculous!

The thing is, I consider Wiz 8 one of the very few games (and I mean very few) in which I am truly expert. I've finished the game close to a dozen times. Yes, I do love the game that much, which means I'll go crawling back to it at some point.

I'm not sure why this particular incident got me so mad. All I know is I said, "That's profanity-verbing profaninty noun!", and immediately quit the game, took the CD out of the drive, thought of destroying the CD now that a digital version is available, surprisingly thought the better of that, and put it petulantly on the shelf instead.

I appreciate everyone's responses so far. Glad to see I'm not alone in the occasional loss of reason. :-)

awh the time honoured RageQuit, oh how we bow to you.

A few days ago, playing Payday. I've clocked 221 hours on that game, and I met someone who was EASILY the most annoying little douche that I have ever played Payday with.
I kept sticking around because the other 2 guys on my crew were great. But this guy would just not shut up. He kept whining, and kept acting like he knew better than the rest of us, when he was obviously pretty new to the game. He spent 90% of the time whining in chat (most of which made very little sense,) and !0% of the time contributing almost nothing. He fucked up every single heist we played, but blamed it on everyone else (mostly on me it seemed). I played with this crew for about an hour before finally cursing at him and leaving.
That might be my only ragequit of 2013.
But was that really a ragequit? Or a sensible quit? I felt like it was somewhere in between.

About 2 years ago, playing Far Cry 1 for the first time, I must have ragequit at least 30 times.

It usually don't do it anymore. Occasionally a RTS will piss me off, because I generally just plain suck at that genre. But that's not too often.
I like to enjoy video games, not hate them. So if I start feeling frustrated, I may take a brief break, take a minute to assess the situation, maybe look at a guide if I really can't figure it out... I try not to let video games "get to me" these days. I've got enough stress in my life, I don't need the one thing that calms me down to stress me out too.

edit - Oh, I just remembered, I ragequit Portal 2's in-game level builder at least once last month. It can get pretty frustrating when your own levels don't turn out the way you want.

That game almost made me rage quit several times and I'm not the rage quitting kind of person.
Sounds like 50% of the people I encounter in online gaming. You get used to it eventually because after some time you become desensitized...numb.

Sorry, but I couldn't disagree more. I think it's the best platformer I've played this year. And the final boss is not impossible, just challenging.

edit: Actually, I'm seeing a lot of titles I thought I'd never see on this thread.
The new XCOM? Hotline Miami? Trine? FTL? Fahrenheit? (well okay, it is a little aggravating here and there) THE NEW XCOM?
I thoroughly enjoyed all of those games from beginning to end. Well, I guess everyone has their own tastes and their level of tolerance.

Exactly. Congratulations on biting through and finishing it nonetheless. :-)

Farenheit has one big problem: QTEs en masse. They really destroy the otherwise nice atmosphere the game creates. Well that, and the story looses out towards the end. All in all it could have been a good game, if they hadn't taken so much effort to increase game time by annoying the players. I imagine it went something like this: "Our game is too short. What can we do?" 'Add some scenes?' "Nah, too costly." 'Some challenging riddles?' "Can't think of any." 'I know, how about we tie every second step to some random QTE. That will cost the player lots of time, our game will appear longer and we don't have to invest any effort on this.' "Great! Let's do that. Problem solved." (and game destroyed, but who cares)

A couple of years ago I ragequitted Daggerfall. There were... a variety of reasons.

My last ragequit was KotOR about 3 years ago; I was replaying for the 4th? time, using mods to try something different, and for some reason the controls of the spacefight minigame were f****ed up. No matter what I did, the mouse wouldnt respond properly, and the ship was destroyed by the most basic fighters in the galaxy. So screw them.

Also I usually "borequit" with several games from bundles. I try them because otherwise it would feel like I could be missing something good, but at some point I say "why am I playing this, I'm wasting my time" and uninstall. Superbrothers Sword & Sworcery was the last.

I almost forgot about this one, yeah, a great idea for a game but an INSANE difficulty ramp.

Also Sol: Exodus. One level that was way too hard and the dialogue was unskippable and somewhat offensive.

I didn't finish the last boss of Secret Agent Clank. Way too hard (my hands were cramping up) and the canned video kept repeating every. single. time. I felt bad about not finishing a R&C game but hey, I had others to play.

Ah, yes. The classic unskippable-cutscene-before-a-major-boss-battle. Always a favorite.