ShadowWulfe: Wishlisted for now.
Where exactly do I start with Sam and Max? My only experience with it is from Jedi Knight.
wolfsite: Sam & Max: Hit the Road is the original game and a great place to start, that is followed up by the Telltale games (Save The World, Beyond Time and Space, The devil's Playhouse), however the original versions are not available with the re-releases the only option, though as you can see these ones are controversial due to changes made by the new developer.
The only other game is Sam & Max: This time it's Virtual which is a VR only game
There is also a 90's Saturday Morning cartoon that ran for one season which does have a number of good episodes considering the time space.
The original versions of Save the World and Beyond Time and Space come with the new versions. You get both in Standard Edition and Game + Soundtrack Bundle.