DesGames123: I have also been experiencing the crashing issue on my main PC, and just like people previously noted it only happens when GOG Galaxy is closed. I was briefly able to get it to work after reinstalling the Nvidia drivers but it stopped booting after that.
However I just installed the game on my Laptop that doesn’t even have GOG Galaxy installed and it is working perfectly fine even with the latest Nvidia drivers and absolutely no GOG processes running.
I don’t think this problem is directly caused by GOG Galaxy but it does seem to fix it for some reason.
Well, I downloaded the newest patch for 2.0 and installed PL just to have it constantly crash at the RedEngine logo. I have heard you and others say that it doesn't crash while using galaxy. Well, two and two equal four. Go into you install directory and delete the Galaxy64.dll. The game launches flawlessly now. Thanks for nothing, GOG.