Whenever I set different resolution than the default one (320*200) the game crashes after a while (a few minutes or so).
Any clues?
(it has nothing to do with sound - I have already tried to disable it at all via setup and no luck)

Well, setting overlay did not help.
However, you were right. After trying OpenGL with no luck either, finally Direct3D saved my day.
Thanks

You're welcome. Good to know you got it working ;)

but then it starts to look horrible and still crash.
so far even to get a level started i have to run at 1440x900, with and without the detail, and trying to run in administrative modes. xp compatible and not.
still crashes either at new game launch, or after i started the level a few moments. im on vista 64 bit, quad core, nvidia setup
im gonna try the game on my GF's pc she is on a dual core, ati setup, vista 32bit and see if i get any better luck there..
If not then I hope Gog.com will address this, because if they don't my next purchases from here might be a little more hesitant.

I run Windows XP 32bit And it hangs on level 3
Help:(
i am running blood2 not the nightmare levels
i asol have the nightmare levels on my pc

I have the same problem too on Windows XP 32 bit.
The game crashes at the end of the first level,
the game crashes after loading a saved game...
Tried with "Disabling DirectX 6 commands" -> didn't worked :(
Please help!

I did the samething Disabling DirectX 6 commands
i even set detail level to low
i even set res to 320X640
EDIT:D3D gets me a blank moniter
And i dont have a idea
=( i am sad
gog (or some one) has to help me
i have windows xp
and a nivida geforce 2 mx\mx
i can play shogo (on software render) fine
it has lithtech (like blood 2)

Try to run the game in Windows 98 compatible mode.
It WORKED on Windows XP 32 bit!
The game is not crashing, you can save now, can change to another resoluton etc.

Still doesn't work.

Blood is crashing after a few seconds of playing a game on my XP system yet plays perfectly on my Vista laptop. I've tried changing the display settings and trying to run it on different compatability modes but no luck.

Must add it is DOSbox that is the problem for some reason, it crashes and says DOSbox has encountered a problem.

The game kept crashing also after changing the display mode, but I've solved the problem disabling one cpu core working with dosbox.
I hope this might help someone! :)

why is this marked as solved it not! win7 and Ive tried everything Ive never had a full hour play though even on lowest res setting, and also it never saves ur setup changes probably something to do with it!