My question is is it the same like for the Steam version or differently. I dont use a Mod Manager.
I wanted to add Auto Loot Mod thats why i ask. Because i couldnt mangage that the Game starts with the mod.

Just create a folder named Mods in the root game folder and drop the contents of the mod's zip file in it. If you have conflicting mods, you will need to employ Script Merger.