OK. Just asked to make sure. That should not be happening. Hmm...

I just got this from GoG because it said XP Vista compatible. I assumed it uses the XP patch the developers made for the game to run on XP without Dosbox.
From Wikipedia: http://en.wikipedia.org/wiki/Redneck_Rampage
"In 2002 the creator of Build engine Ken Silverman wrote a VESA 2.0 patch in order to make all Build-powered games compatible with NT/2000/XP."
Thats what i want.. it would be so much better than DosBox. I am shocked GoG used DosBox instead of this!
But if posssible I dont want to use DosBox.. i want to try the patch. Does anyone know where I can find this patch?
EDIT:
I found it!!!
You can get the patch here: http://advsys.net/ken/build.htm
Scroll down a bit and you will see:
" VESA 2.0 patch for Windows NT/2000/XP (09/21/2002 )"
I havent tried this yet. I will test it out and report back.

I also didn't want to use DOSBox for this game as it runs terribly slow on my netbook. I used the VESA 2.0 patch and VDMSound and it works relly great even on my netbook.
See the last post in the following thread to figure out how to launch it: http://forums.afterdawn.com/thread_view.cfm/381884

There is one other solution, an eduke32 fork called erampage, you all might want to consider. It is still in development so it's even more beta then eduke32 is but runs very well in my short tests.
http://www.jonof.id.au/forum/index.php?topic=1798.0
Download link in that forum post, but in case you want to cut ot the chase.
http://code.google.com/p/erampage/downloads/list
Edit: Didn't see this post till now there an already setup pack here just needs the grp files.
http://www.jonof.id.au/forum/index.php?topic=1798.msg12654#msg12654

BOOZE:
What key have you assigned whiskey to? I had the same problem (i.e. whiskey used automatically when my health goes down) when I changed the movement controls to W, A, S, D (instead of default arrows) and unintentionally left the 'W' key assigned to whiskey. You have to either get maximally drunk, I mean as to the point of puking, or use chips and pork pies to make the booze-counter go down. You can also wait a few minutes and e.g. go for a smoke break. ;)
MOUSE LOOK:
You have to do a few things in order to get this right. In the setup program, see Control Setup and go to Advanced Mouse Setup (something like that). There, you can reverse Y axis and assign actions to each mouse axis (or switch them off, in case your character still moves forward and backward when you slide your mouse up and down). Use the key "U" to switch on mouse targeting, "I" (afair) to turn on crosshair.
edit, VISTA:
It works on Vista pretty well, even though I got a fairly old setup (Pavillion dv9500).