As you first enter the Arboretum by climbing out of the maintenance tunnel, the sprinkler system is nearby. Next to it is a locked shed with a non-functional keypad. Has anyone managed to get inside without hacking or other human abilities?

I can go around to the side and climb from the hedge to the roof. But I can't target the door button with Remote Manipulation. If I morph into small object, I just roll around in mid-air on top of the slats, though it seems I should fall through the gaps.

You cannot go in there without hacking the door lock unfortunately.

Thank you for the reply.

My initial impression was that there are always several ways to enter or access something. After multiple playthroughs, I realized there are multiple keypads and terminals that can only be accessed by hacking.

you're right on both counts, but also keep in mind that for some areas you'll also need ID cards or such to access rooms or to use with keypads. Explore everywhere in every way, the game's rewarding like that :D

The two are mutually exclusive... Rest assured, I've looked in every nook and cranny!

Ahh, gotcha.

Also, nice completion score! I'm brand new to this thing, can't wait to 100% this :D

Thanks and good luck. Some unsolicited tips that may be helpful:
* Achievements that require you to get all of something actually require you to get most.
* It took me too long to figure this out, but recycler grenades can be used to destroy obstacles that require Leverage to move.
* At the same time, careful where you toss those. You could accidentally recycle a dead body and lock yourself out of the achievement for finding every crew member.
* One crew member can never be found because she's only mentioned and doesn't actually appear in the game. Another crew member you can only talk to, so don't worry about her for the achievement where you... uh... decide not to be so nice to everyone. Early on, you'll notice people locked in the IT closet. Don't waste your time trying to get to them; they can only be reached late in the game in the aforementioned type of playthrough.
* Always save your game before entering a new area. People can die for various reasons and that can lock you out of an achievement.
* For some bizarre reason, you're only allowed 20 manual saves. You may want to create backups before overwriting your set of saves.
* Difficulty has no bearing on achievements. Go ahead and set it to easy mode for a No Needles run.
* Edit: And one more thing. When you're given the quest to kill someone, you can safely follow it through to the end without attacking. It won't void the Do No Harm achievement that way.

Excellent advice, duly noted. Thanks!