I can run the game in VR by right clicking on NMS and then Other > OpenVR, but is there a way to run this without SteamVR? Also when I add it through the Oculus library, it still runs it through SteamVR. If someone could share share their experience that would be great.

Wait, what VR do you have? Is it an Oculus type VR?

You shouldn`t be running it through Steam at all. At least I don`t.

It looks like there is no other option.
It run very nicely on my set up but unfortunately it has to start up via Steam VR.
I know it's shit but I didn't expect any better. I'm happy that it works at all.

Yes, I have an Oculus Rift S. How do you do it?

I click the No Mans Sky VR in the list in Windows (lower left corner), No Mans Sky VR option.

I have a No Mans Sky (OpenVR). And yes it runs it trough Steam. Weird. Maybe because I started it up for the first time through OpenVR. Anyway, thanks.
http://prntscr.com/ostb8i

See my new thread on how to do it. You`ll need to change a Steam VR setting.

Sorry about the mix up.

crea un acceso directo al ejecutable con los parametros -HmdEnable 1
ej: "C:\Games\No Man's Sky\Binaries\NMS.exe" -HmdEnable 1