Crossfire is ATI's way of using 2 graphic cards as one, equivalent to NVIDIA's SLI.
As for the SingleGPUExe (or however that option it's called), it should exist somewhere in the graphic card's options (Catalyst Control Center or NVIDIA's equivalent)
It has been quite some time since I've last played 1.12, so I'm not sure if the ability to play in a window exists for that version, but if it does then usually windowed mode solves this as well, though with the obvious problems windowed mode has.
Hope this helps you play this excellent game.