https://www.youtube.com/watch?v=sJOrDhghr60 These steps are pretty much needed to play FNV at all, yet crashes with even these are somewhat common.
Just skip "BSA decompressor", I think it causes more problems than it does help, use "Vorbis libraries" instead (only music changes, without graphics BSA changes, which causes problems, such as missing graphics), even with only music changes you will notice better performance boost than any other mod out there.
If you just downloaded GoG game and started play without mods etc, then there will be crashes so often, that I couldn't care to play at all, with changes / mods from that video, it actually play quite nice (few crashes that still happen, mostly when fast travel etc)
Personally my game performance is enough for my needs (8250U, 8GB RAM, SSD, MX150 GPU) on 1080p gameplay, just remember save often.