Stevedog13: The file you want to run is called BSETUP.EXE but you need to run it in DosBox as it won't run in Windows.
The better option is to use Eduke
http://eduke32.com/ From the Website:
Much like the Duke himself, our inflated egos say we're the best, period. Here's why:
EDuke32 runs natively without relying on emulation of any kind
EDuke32 runs at crazy resolutions like 3072x2304.
EDuke32 allows you to choose between two different hardware accelerated OpenGL renderers, or the classic, warped software mode you grew up with
EDuke32 fixes an insane amount of programming errors which were harmless in the days of DOS but are fatal with modern protected memory models; translation: EDuke32 crashes less
EDuke32 has been the only actively developed and maintained Duke3D port for years
EDuke32 features Plagman's incredible "Polymer" renderer as a replacement for Ken Silverman's "Polymost" renderer
EDuke32 has a huge number of new extensions to the game's scripting system, allowing gameplay mods that rival even modern games.
EDuke32 runs the HRP with support for all features, most of which require EDuke32; no other port can run the HRP with all features enabled
EDuke32 adds a full-featured console, including Quake-style key bindings, command aliases, advanced tab completion, comprehensive command history, colored text and more
EDuke32 has hundreds of code rewrites, optimizations and fixes for rare or annoying bugs in the original code
EDuke32 adds tons of optional new features that make the player's life easier including modern status display/HUD, support for loading mods from the startup window, and modern, WSAD-based controls with thoroughly reworked mouse aiming
EDuke32 supports Ogg Vorbis sound and music
EDuke32 is developed by people who have been in the Duke3D scene since the beginning
EDuke32 lets you play that game called 'NAM' you saw at the dollar store 10 years ago
EDuke32 makes sandwiches!
I Download it eduke32 and it doesn´t work like I want to.
ThE game is running Fine even without Eduke, but I can´t Change the controll Settings on my keyboard!!!
ANd if I try to run the eduke it say´s there are no duke 3d version on the computer even though I download it from gog and installed , so what is the problem!?
ANd please somebody tell me how to change the keyboard controll settings that is my main problem!!!!!