sometimes when i highlihght a item to take either on the ground or in a container i just hear the click sound and i have to multi click on the item to finally get it to my inventory. Anyone else have this issue?

Probably due to the multithreading issue.

You could try my guide:

https://www.gog.com/forum/divinity_series/divine_divinity_smooth_fps_using_dgvoodoo_2_guide/post1

The things described in Step 4 should solve your problem.