Okay so this problem is pretty weird, couldn't find any information anywhere on it...So I'm playing the new Enhanced Edition on 6025 x 1200 (3 screens), same way I played the original before enhanced...everything plays okay besides the fact I can't see ANY items when using alt on my main screen...they show up on both side screens but the second they enter the middle screen for pickup they disappear...Now since I'm playing with a buddy and this is basically diablo with shared item pickups, I'm getting WAAAY behind in gold and equipment...anybody else having this issue? Or know of any solutions? I don't have this issue when I use only 1 screen, all items show but why have 3 if I'm not gonna use them right? I'll post some pics later if they help, @ work atm :P

Invisible items seems to be a thing that they are working on. Today GOG released a patch which was released on Steam yesterday which half solves this. Today another update has been released on Steam which should fully solve it, so you gotta wait for GOG to release their update. This will probably be tomorrow somewhere.

Version 2.0.99.10 (Now on GOG)

Fix for crashing book UI in 4K resolutions
Fix for rare case where items could become invisible. Items will be restored.
Fix for backspace not working in chat
Added error message for windows vista and windows 7 without SP1
Fixed blocking issue in French that would block progress in combat
Fixed incorrect text in Russian in chat window
Fixed direct connect issue when no internet connection
Fixed equipping from other inventory

Version 2.0.99.113 (Now on Steam)
Fix for invisible items in containers
Fix for Crafting interface in Polish
Fix for book interface in Russian
Fix for sometimes having to click multiple times to pick up items
Fix for not being able to assign skill points under certain conditions

Hope these solve your issues.

2.0.99.113 version now with 4 player mod...still same problem :( It's aggravating because I've tried all sorts of configs in video - messing with shadows, resolution sizes, fake fullscreen, windowed, etc. Still no luck :( I've since had to put it on 1920x1200 just so I don't miss any items. Can't really find a similar issue anywhere else either and I KNOW people have to be using their surround setup on this beautiful game....here's hoping to a fix soon.