My cyberpunk 2077 game is still on patch 1.22 and for some reason it doesn't download and install the new updates until patch 1.52. Does anyone know if this download can be done manually? Could it be due to lack of memory or something?

You use Galaxy, right? Cause, there is never be 1.22-1.5 patch (its digital distribution patches, they never cumulitive).
Still it need some free space on both logic disks, for Galaxy version too.

Around 50 Gb is minimum in any case. And way moe for offline patches.

My update was frozen the first couple days of the patch. I tried it again last night, and it finally patched the game, but took 2 hours to get through all the file updates. You might want to try again.