I don't have it quite worked out myself, but there's a lot here:

http://forums.screwflystudios.com/index.php/board,2.60.html

And other than that, it looks like random chance can really screw you over. This post seems to have more insight than most:

http://forums.screwflystudios.com/index.php/topic,256.0.html

As far as I can tell, the game is sort of rigged to be a Survival-Horror-Casino-Blue's Clues game that pretty much invalidates base building as a viable strategy, which is kind of a shame. I hope future patches can change this to a meaningful extent.

Thanks ! That does help .

Interestingly enough, I did find that following some of the advice from the Zombie Survival Guide (a parody book) actually worked well, insofar as urban scenarios are concerned. In Classic mode, you don't want t barricade and hole up until you know the rescue location- otherwise it's breach, search, move, breach. I haven't won yet, but I've gotten pretty close. Roadkill, on the other hand, works a little differently--- I'd say you still need to stay on the move, but once you find the vehicle location, go back to it and barricade yourself once you have all the missing parts while you repair the vehicle.
I was doing very well in Roadkill, until Super Zombie showed up, I decided to run--- and, of course, my survivors scattered to the four winds and were all massacred trying to breach different buildings.
It would be nice if you could tell the game *where* you want all of your survivors to run, as opposed to them scattering to the four winds to their deaths.

After doing some research through this and the official forums I found for classic is to breach, do a single search, and repeat with only one building as a safe house. Contrary to what others of said I've had worse luck with roadkill mode, but depending on the group a similar hit and run tactic can work at a slower pace.

We've made some changes in the latest patch so that you'll have more information at your disposal to make decisions, including an assessment of your chances when facing the likes of the lynch mob, girl scout family and the super zombie. Investigating is also much, much more accurate now -- one survivor with a pair of binoculars or two survivors should be enough to spot most of the zombies at a location.

Hopefully GOG will have the updated version available for you guys soon.

Just downloaded it, thanks. Going to give this a go later tonight.

Would it be possible to make the saving system an option? I like the old way as it's faster. I can understand needing to change it to enable mid game saves but I like being able to exit the game know it was saved automatically.

Thank you for continuing to improve Zafehouse Diaries!