danq333: Yes I am running profiler. But before installing it, the mouse controls were also just as bad. I don't know how people can play this game all the way through. I can barely hit a ship.
It is possible that you are not experiencing the same problem that I was. When I say that Profiler interfered with the joystick controls, I mean that the controls were utterly broken, making it near impossible to steer in certain directions.
As for mouse controls, I would personally never use them, even if they work well. I have been using joysticks since I first started gaming, even if they [url=http://en.wikipedia.org/wiki/File:ColecoVision-Controller-FR.jpg]looked like phones[/url] at the time.
Even after I solved the joystick problem, I found WC4 to be a bit more difficult than WC3. It is certainly more fast-paced, and places higher demands on the player's reflexes. Some ships have aim-assist which helps a bit, but you will often fly ships that do not.