Just wondering if anyone would be able to help me here, every time I open TR 3 a dialogue box pops up saying "Tomb Raider 3 Failed to Initialise, Please Run Set-Up", I dont understand why, I have un-installed and re-installed the game several times, and I have also tried running the set-up again. Tomb Raider 1 and 2 work, I'm disappointed because when you buy a game you expect it to work and if there are multiple games, you expect them all to work. someone please help

Welcome,
I suggest you to contact support. Meanwhile you could add more informations regarding the issue.
Which OS do you use? How do you launch the game? And so on...

Did you get a fix? I am getting the same message. I am running XP.

Of course it worked... :)
I got soooo used to not using the start menu that I actually did not even realize what people were saying to do to fix this. I was right clicking the file and going into properties instead of looking it up under the GOG tab in the start menu. Don't ask.... we will just say that my brain stopped working for a little while there. It is working fine now (Tomb Raider, not my brain).

Excellent, glad you got it working :)

i've the same problem with this game,please,can someones say how to run the Tomb Raider 3 setup from the Tools folder in your Start menu?

Assuming you're on windows 7 if not it won't be too different perform the following in the following order:

Left click 'start' /windows icon on bottom left -> Press 'All programs' -> Find the folder 'GOG.com' and left click it -> Left click 'Tomb Raider 1+2+3' -> Left click 'Tomb Raider 3' -> And finally left click 'setup'.