Yes I had 5 crashes today which is more than the previous 60+ hours I've played combined. I have other issues too, the characters clothes are wet even when it isn't raining, Shadowplay no longer works, launching it from steam as a non-steam game no longer works, I have framerate drops were I had none before and overall the game just feels broken as shit. Considering what an exhaustive patch 1.10 was I'm sorry to say it is by far the worst out of the 3 patches I've had since starting the game.
I feel like I'm playing the game at launch as opposed to months later after the kinks have been worked out. I'm thinking of stopping until the next patch its so bad.