This is a doozie! I've had this issue with several missions now where I'm doing a mission and the NPC will just stand there with either -1 above their head or their level with the health bar empty. They don't move or do anything and I can't kill them or get any loot and the missions are unable to complete successfully cause of it. I'm at a loss of what to do and it is extremely annoying! I don't think i'll be able to finish the game if this keeps up.

another image from another mission that's glitching..... please help!!! :(

This is a bug that was fixed in patch 1.11. Patch your game.

It is patched! :(

turn off antivirus in galaxy go to more manage verify/repair wait for repair and download new files when its done you can turn on you antivirus after that load a save before travel to skellige it should help

This seems to have fixed this issue.

http://forums.cdprojektred.com/threads/61550-BUG-Please-fix-1-hp-enemies-as-soon-as-possible

But it was patched! GOG kept saying that the game was "up to date" . I also did the verify/fix thing several times and each time it said it was up to date. This only fixed when i uninstalled GOG and manually installed the DLC content again.