peternl: Pls remember when install driver first remove it through safemode with DDU(from guru3D) this way you have absolute clean install and will not hve errors because still old parts driver on your PC because there all gone. Read instructions its easy in use can be used both for AMD/Nvidia.
Bleed: Actually those days are long past, nowadays you don't even need to reboot. Just install the driver and let it replace the old one, you'll notice the screen go blank then all done.
There are no more "old parts" left behind so don't waste your time trying to uninstall or going into safe mode.
Source :
http://www.howtogeek.com/171816/htg-explains-do-you-need-to-use-a-driver-cleaner-when-upgrading-hardware-drivers/
I'd recommend any AMD user install these beta drivers since you're sure to get a performance increase, I know i did.
While I agree that installing new drivers without uninstalling old ones should work properly in this day and age, there WILL be "useless scrap" left behind. On my current PC, I had drivers for a GTX 760, HD 7870 and R9 290, all of which were uninstalled with their respective tools (Catalyst / NVidia Experience).
A couple months ago, I decided to do a clean uninstall of old drivers prior to installing those for my new R9 285 and managed to save ~7 GB of memory. So old drivers do in fact leave unneeded scrap. Not function-wise, but storage-wise.